{"id":13496,"date":"2025-10-07T16:33:39","date_gmt":"2025-10-07T14:33:39","guid":{"rendered":"https:\/\/caimed.de\/?page_id=13496"},"modified":"2025-10-07T16:42:11","modified_gmt":"2025-10-07T14:42:11","slug":"3-fragen-an-prof-dr-andriy-goychuk","status":"publish","type":"page","link":"https:\/\/caimed.de\/en\/3-fragen-an-prof-dr-andriy-goychuk\/","title":{"rendered":"3 Fragen an Prof. Dr. Andriy Goychuk"},"content":{"rendered":"<div data-colibri-id=\"13496-c1\" class=\"style-7082 style-local-13496-c1 position-relative\">\n  <!---->\n  <div data-colibri-component=\"section\" data-colibri-id=\"13496-c10\" id=\"reusable-sections-2\" class=\"h-section h-section-global-spacing d-flex align-items-lg-center align-items-md-center align-items-center style-7091 style-local-13496-c10 position-relative\">\n    <!---->\n    <!---->\n    <div class=\"h-section-grid-container h-section-boxed-container\">\n      <!---->\n      <div data-colibri-id=\"13496-c11\" class=\"h-row-container gutters-row-lg-0 gutters-row-md-0 gutters-row-2 gutters-row-v-lg-0 gutters-row-v-md-0 gutters-row-v-2 style-7092 style-local-13496-c11 position-relative\">\n        <!---->\n        <div class=\"h-row justify-content-lg-start justify-content-md-start justify-content-start align-items-lg-stretch align-items-md-stretch align-items-stretch gutters-col-lg-0 gutters-col-md-0 gutters-col-2 gutters-col-v-lg-0 gutters-col-v-md-0 gutters-col-v-2\">\n          <!---->\n          <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-7093-outer style-local-13496-c12-outer\">\n            <div data-colibri-id=\"13496-c12\" class=\"d-flex h-flex-basis h-column__inner h-px-lg-0 h-px-md-0 h-px-0 v-inner-lg-0 v-inner-md-0 v-inner-0 style-7093 style-local-13496-c12 position-relative\">\n              <!---->\n              <!---->\n              <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-center align-self-md-center align-self-center\">\n                <!---->\n                <div data-colibri-id=\"13496-c13\" class=\"style-7094 style-local-13496-c13 position-relative h-element\">\n                  <!---->\n                  <div class=\"h-global-transition-all\"><div id='colibri-13496-c13' class='breadcrumb-wrapper'>    <style type=\"text\/css\">\n        \/* breadcrumb separator symbol *\/\n\n        #colibri-13496-c13        .colibri-breadcrumb > li + li:before {\n            content: \"|\";\n            white-space: pre;\n        }\n    <\/style>\n\n    \n    <div class=\"colibri-13496-c13-dls-wrapper breadcrumb-items__wrapper\">\n                <ol class=\"breadcrumb colibri-breadcrumb\"><li class=\"breadcrumb-item\"><a href=\"https:\/\/caimed.de\/en\/\">Home<\/a><\/li><\/ol>    <\/div>\n    <\/div><\/div>\n                <\/div>\n              <\/div>\n            <\/div>\n          <\/div>\n          <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-7095-outer style-local-13496-c14-outer\">\n            <div data-colibri-id=\"13496-c14\" class=\"d-flex h-flex-basis h-column__inner h-px-lg-0 h-px-md-0 h-px-0 v-inner-lg-0 v-inner-md-0 v-inner-0 style-7095 style-local-13496-c14 position-relative\">\n              <!---->\n              <!---->\n              <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-start align-self-md-start align-self-start\">\n                <!---->\n                <div data-colibri-id=\"13496-c15\" class=\"style-7096 style-local-13496-c15 position-relative h-element\">\n                  <!---->\n                <\/div>\n              <\/div>\n            <\/div>\n          <\/div>\n          <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-7097-outer style-local-13496-c16-outer\">\n            <div data-colibri-id=\"13496-c16\" class=\"d-flex h-flex-basis h-column__inner h-px-lg-0 h-px-md-0 h-px-0 v-inner-lg-0 v-inner-md-0 v-inner-0 style-7097 style-local-13496-c16 position-relative\">\n              <!---->\n              <!---->\n              <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-start align-self-md-start align-self-start\">\n                <!---->\n                <div data-colibri-id=\"13496-c17\" class=\"h-global-transition-all h-heading style-7098 style-local-13496-c17 position-relative h-element\">\n                  <!---->\n                  <div class=\"h-heading__outer style-7098 style-local-13496-c17\">\n                    <!---->\n                    <!---->\n                    <h3 class=\"\">3 questions for...<\/h3>\n                  <\/div>\n                <\/div>\n              <\/div>\n            <\/div>\n          <\/div>\n        <\/div>\n      <\/div>\n      <div data-colibri-id=\"13496-c18\" class=\"h-row-container gutters-row-lg-1 gutters-row-md-1 gutters-row-2 gutters-row-v-lg-1 gutters-row-v-md-1 gutters-row-v-2 style-7099 style-local-13496-c18 position-relative\">\n        <!---->\n        <div class=\"h-row justify-content-lg-center justify-content-md-center justify-content-center align-items-lg-stretch align-items-md-stretch align-items-stretch gutters-col-lg-1 gutters-col-md-1 gutters-col-2 gutters-col-v-lg-1 gutters-col-v-md-1 gutters-col-v-2\">\n          <!---->\n          <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-7100-outer style-local-13496-c19-outer\">\n            <div data-colibri-id=\"13496-c19\" class=\"d-flex h-flex-basis h-column__inner h-px-lg-2 h-px-md-2 h-px-2 v-inner-lg-2 v-inner-md-2 v-inner-2 style-7100 style-local-13496-c19 position-relative\">\n              <!---->\n              <!---->\n              <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-start align-self-md-start align-self-start\">\n                <!---->\n                <div data-colibri-id=\"13496-c20\" class=\"d-block style-7101 style-local-13496-c20 position-relative h-element\">\n                  <!---->\n                  <div class=\"h-image__frame-container-outer\">\n                    <div class=\"h-image__frame-container\">\n                      <!---->\n                      <!---->\n                      <img decoding=\"async\" width=\"400\" height=\"400\" data-src=\"https:\/\/caimed.de\/wp-content\/uploads\/2025\/10\/Andriy-Goychuck-1.png\" class=\"wp-image-13488 style-7101-image style-local-13496-c20-image lazyload\" alt=\"\" data-srcset=\"https:\/\/caimed.de\/wp-content\/uploads\/2025\/10\/Andriy-Goychuck-1.png 400w, https:\/\/caimed.de\/wp-content\/uploads\/2025\/10\/Andriy-Goychuck-1-12x12.png 12w\" data-sizes=\"(max-width: 400px) 100vw, 400px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 400px; --smush-placeholder-aspect-ratio: 400\/400;\" \/>\n                      <div class=\"h-image__frame h-hide-lg h-hide-md h-hide-sm style-7101-frameImage style-local-13496-c20-frameImage\"><\/div>\n                    <\/div>\n                  <\/div>\n                <\/div>\n              <\/div>\n            <\/div>\n          <\/div>\n          <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-7102-outer style-local-13496-c21-outer\">\n            <div data-colibri-id=\"13496-c21\" class=\"d-flex h-flex-basis h-column__inner h-px-lg-2 h-px-md-2 h-px-2 v-inner-lg-2 v-inner-md-2 v-inner-2 style-7102 style-local-13496-c21 position-relative\">\n              <!---->\n              <!---->\n              <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-start align-self-md-start align-self-start\">\n                <!---->\n                <div data-colibri-id=\"13496-c22\" class=\"h-global-transition-all h-heading style-7103 style-local-13496-c22 position-relative h-element\">\n                  <!---->\n                  <div class=\"h-heading__outer style-7103 style-local-13496-c22\">\n                    <!---->\n                    <!---->\n                    <h3 class=\"\">Prof. Dr. Andriy Goychuk<\/h3>\n                  <\/div>\n                <\/div>\n                <div data-colibri-id=\"13496-c23\" class=\"h-text h-text-component style-7104 style-local-13496-c23 position-relative h-element\">\n                  <!---->\n                  <!---->\n                  <div class=\"\">\n                    <p>Groupleader<\/p>\n                  <\/div>\n                <\/div>\n                <div data-colibri-id=\"13496-c24\" class=\"h-text h-text-component style-7105 style-local-13496-c24 position-relative h-element\">\n                  <!---->\n                  <!---->\n                  <div class=\"\">\n                    <p>Prof. Dr. Andriy Goychuk researches the self-organization of living matter across various scales \u2013 from inflammatory processes and cell dynamics at the tissue level to organization in the cell nucleus and the dynamics of proteins. A focus of his work is the development of numerical methods and theoretical models based on biophysics, statistical mechanics, fluid mechanics, and nonlinear dynamics. After completing his doctorate in physics at Ludwig Maximilian University in Munich in 2021 on cell movements and protein patterns, he conducted postdoctoral research at the Massachusetts Institute of Technology. His work on chromatin organization and biomolecular condensates was funded by the European Molecular Biology Organization. Since 2025, he has led a research group at CAIMed and the Helmholtz Centre for Infection Research.<\/p>\n                  <\/div>\n                <\/div>\n              <\/div>\n            <\/div>\n          <\/div>\n        <\/div>\n      <\/div>\n      <div data-colibri-id=\"13496-c25\" class=\"h-row-container gutters-row-lg-2 gutters-row-md-2 gutters-row-0 gutters-row-v-lg-2 gutters-row-v-md-2 gutters-row-v-2 style-7106 style-local-13496-c25 position-relative\">\n        <!---->\n        <div class=\"h-row justify-content-lg-center justify-content-md-center justify-content-center align-items-lg-stretch align-items-md-stretch align-items-stretch gutters-col-lg-2 gutters-col-md-2 gutters-col-0 gutters-col-v-lg-2 gutters-col-v-md-2 gutters-col-v-2\">\n          <!---->\n          <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-7107-outer style-local-13496-c26-outer\">\n            <div data-colibri-id=\"13496-c26\" class=\"d-flex h-flex-basis h-column__inner h-px-lg-2 h-px-md-2 h-px-2 v-inner-lg-2 v-inner-md-2 v-inner-2 style-7107 style-local-13496-c26 position-relative\">\n              <!---->\n              <!---->\n              <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-start align-self-md-start align-self-start\">\n                <!---->\n                <div data-colibri-id=\"13496-c27\" class=\"style-7108 style-local-13496-c27 position-relative h-element\">\n                  <!---->\n                <\/div>\n              <\/div>\n            <\/div>\n          <\/div>\n        <\/div>\n      <\/div>\n      <div data-colibri-id=\"13496-c28\" class=\"h-row-container gutters-row-lg-0 gutters-row-md-0 gutters-row-0 gutters-row-v-lg-0 gutters-row-v-md-0 gutters-row-v-0 style-7109 style-local-13496-c28 position-relative\">\n        <!---->\n        <div class=\"h-row justify-content-lg-center justify-content-md-center justify-content-center align-items-lg-stretch align-items-md-stretch align-items-stretch gutters-col-lg-0 gutters-col-md-0 gutters-col-0 gutters-col-v-lg-0 gutters-col-v-md-0 gutters-col-v-0\">\n          <!---->\n          <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-7110-outer style-local-13496-c29-outer\">\n            <div data-colibri-id=\"13496-c29\" class=\"d-flex h-flex-basis h-column__inner h-px-lg-2 h-px-md-2 h-px-2 v-inner-lg-2 v-inner-md-2 v-inner-2 style-7110 style-local-13496-c29 position-relative\">\n              <!---->\n              <!---->\n              <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-center align-self-md-center align-self-center\">\n                <!---->\n                <div data-colibri-id=\"13496-c30\" class=\"h-global-transition-all h-heading style-7111 style-local-13496-c30 position-relative h-element\">\n                  <!---->\n                  <div class=\"h-heading__outer style-7111 style-local-13496-c30\">\n                    <!---->\n                    <!---->\n                    <h4 class=\"\">1.\n                      <br>\n                    <\/h4>\n                  <\/div>\n                <\/div>\n              <\/div>\n            <\/div>\n          <\/div>\n          <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-7112-outer style-local-13496-c31-outer\">\n            <div data-colibri-id=\"13496-c31\" class=\"d-flex h-flex-basis h-column__inner h-px-lg-0 h-px-md-0 h-px-0 v-inner-lg-0 v-inner-md-0 v-inner-0 style-7112 style-local-13496-c31 position-relative\">\n              <!---->\n              <!---->\n              <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-center align-self-md-center align-self-center\">\n                <!---->\n                <div data-colibri-id=\"13496-c32\" class=\"h-global-transition-all h-heading style-7113 style-local-13496-c32 position-relative h-element\">\n                  <!---->\n                  <div class=\"h-heading__outer style-7113 style-local-13496-c32\">\n                    <!---->\n                    <!---->\n                    <h4 class=\"\">You work at the intersection of physics, biology, and medicine. What opportunities does this interdisciplinary perspective open up for medical research?<\/h4>\n                  <\/div>\n                <\/div>\n              <\/div>\n            <\/div>\n          <\/div>\n        <\/div>\n      <\/div>\n      <div data-colibri-id=\"13496-c33\" class=\"h-row-container gutters-row-lg-0 gutters-row-md-0 gutters-row-0 gutters-row-v-lg-0 gutters-row-v-md-0 gutters-row-v-0 style-7114 style-local-13496-c33 position-relative\">\n        <!---->\n        <div class=\"h-row justify-content-lg-center justify-content-md-center justify-content-center align-items-lg-stretch align-items-md-stretch align-items-stretch gutters-col-lg-0 gutters-col-md-0 gutters-col-0 gutters-col-v-lg-0 gutters-col-v-md-0 gutters-col-v-0\">\n          <!---->\n          <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-7115-outer style-local-13496-c34-outer\">\n            <div data-colibri-id=\"13496-c34\" class=\"d-flex h-flex-basis h-column__inner h-px-lg-0 h-px-md-0 h-px-0 v-inner-lg-0 v-inner-md-0 v-inner-0 style-7115 style-local-13496-c34 position-relative\">\n              <!---->\n              <!---->\n              <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-start align-self-md-start align-self-start\">\n                <!---->\n                <div data-colibri-id=\"13496-c35\" class=\"h-icon style-7116 style-local-13496-c35 position-relative h-element\">\n                  <!----><span class=\"h-svg-icon h-icon__icon style-7116-icon style-local-13496-c35-icon\"><!--Icon by Material Icons (https:\/\/material.io)--><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" id=\"format_quote\" viewbox=\"0 0 512 512\"><path d=\"M299 363l42-86h-64V149h128v128l-42 86h-64zm-171 0l43-86h-64V149h128v128l-43 86h-64z\"><\/path><\/svg><\/span><\/div>\n              <\/div>\n            <\/div>\n          <\/div>\n          <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-7112-outer style-local-13496-c36-outer\">\n            <div data-colibri-id=\"13496-c36\" class=\"d-flex h-flex-basis h-column__inner h-px-lg-0 h-px-md-0 h-px-0 v-inner-lg-0 v-inner-md-0 v-inner-0 style-7112 style-local-13496-c36 position-relative\">\n              <!---->\n              <!---->\n              <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-center align-self-md-center align-self-center\">\n                <!---->\n                <div data-colibri-id=\"13496-c37\" class=\"h-text h-text-component style-7117 style-local-13496-c37 position-relative h-element\">\n                  <!---->\n                  <!---->\n                  <div class=\"\">\n                    <p>Mathematical and biophysical modeling can help us understand the principles guiding the organization of cells and tissues, and how this organization controls function. Conversely, these same principles provide an opportunity to uncover how and why function is perturbed during diseases. For example, I recently learned during a visit that very different diseases (e.g., viral infections such as Zika and certain genetic defects) can have similar phenomenologies (in that particular example, a change in the architecture of the nuclear pore complex) and clinical outcomes (in that case, developmental delays). I think that shared principles of organization, or shared failure points, can explain why different diseases can have similar features. Beyond explaining the \"how\" and \u201cwhy\u201d, modeling also allows testing the feasibility of a potential intervention. The broader vision of my group is to integrate the physical principles of biological organization to understand how cell and tissue homeostasis are perturbed by the expression of viral proteins during infection, cytokine signaling during inflammation, and restored upon recovery.<\/p>\n                  <\/div>\n                <\/div>\n              <\/div>\n            <\/div>\n          <\/div>\n        <\/div>\n      <\/div>\n      <div data-colibri-id=\"13496-c38\" class=\"h-row-container gutters-row-lg-0 gutters-row-md-0 gutters-row-0 gutters-row-v-lg-0 gutters-row-v-md-0 gutters-row-v-0 style-7109 style-local-13496-c38 position-relative\">\n        <!---->\n        <div class=\"h-row justify-content-lg-center justify-content-md-center justify-content-center align-items-lg-stretch align-items-md-stretch align-items-stretch gutters-col-lg-0 gutters-col-md-0 gutters-col-0 gutters-col-v-lg-0 gutters-col-v-md-0 gutters-col-v-0\">\n          <!---->\n          <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-7110-outer style-local-13496-c39-outer\">\n            <div data-colibri-id=\"13496-c39\" class=\"d-flex h-flex-basis h-column__inner h-px-lg-2 h-px-md-2 h-px-2 v-inner-lg-2 v-inner-md-2 v-inner-2 style-7110 style-local-13496-c39 position-relative\">\n              <!---->\n              <!---->\n              <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-center align-self-md-center align-self-center\">\n                <!---->\n                <div data-colibri-id=\"13496-c40\" class=\"h-global-transition-all h-heading style-7111 style-local-13496-c40 position-relative h-element\">\n                  <!---->\n                  <div class=\"h-heading__outer style-7111 style-local-13496-c40\">\n                    <!---->\n                    <!---->\n                    <h4 class=\"\">2.<\/h4>\n                  <\/div>\n                <\/div>\n              <\/div>\n            <\/div>\n          <\/div>\n          <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-7112-outer style-local-13496-c41-outer\">\n            <div data-colibri-id=\"13496-c41\" class=\"d-flex h-flex-basis h-column__inner h-px-lg-0 h-px-md-0 h-px-0 v-inner-lg-0 v-inner-md-0 v-inner-0 style-7112 style-local-13496-c41 position-relative\">\n              <!---->\n              <!---->\n              <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-center align-self-md-center align-self-center\">\n                <!---->\n                <div data-colibri-id=\"13496-c42\" class=\"h-global-transition-all h-heading style-7113 style-local-13496-c42 position-relative h-element\">\n                  <!---->\n                  <div class=\"h-heading__outer style-7113 style-local-13496-c42\">\n                    <!---->\n                    <!---->\n                    <h4 class=\"\">What fascinates you about describing biological systems with physical principles \u2013 and what new perspectives does this create for research within CAIMed?<\/h4>\n                  <\/div>\n                <\/div>\n              <\/div>\n            <\/div>\n          <\/div>\n        <\/div>\n      <\/div>\n      <div data-colibri-id=\"13496-c43\" class=\"h-row-container gutters-row-lg-0 gutters-row-md-0 gutters-row-0 gutters-row-v-lg-0 gutters-row-v-md-0 gutters-row-v-0 style-7114 style-local-13496-c43 position-relative\">\n        <!---->\n        <div class=\"h-row justify-content-lg-center justify-content-md-center justify-content-center align-items-lg-stretch align-items-md-stretch align-items-stretch gutters-col-lg-0 gutters-col-md-0 gutters-col-0 gutters-col-v-lg-0 gutters-col-v-md-0 gutters-col-v-0\">\n          <!---->\n          <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-7115-outer style-local-13496-c44-outer\">\n            <div data-colibri-id=\"13496-c44\" class=\"d-flex h-flex-basis h-column__inner h-px-lg-0 h-px-md-0 h-px-0 v-inner-lg-0 v-inner-md-0 v-inner-0 style-7115 style-local-13496-c44 position-relative\">\n              <!---->\n              <!---->\n              <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-start align-self-md-start align-self-start\">\n                <!---->\n                <div data-colibri-id=\"13496-c45\" class=\"h-icon style-7116 style-local-13496-c45 position-relative h-element\">\n                  <!----><span class=\"h-svg-icon h-icon__icon style-7116-icon style-local-13496-c45-icon\"><!--Icon by Material Icons (https:\/\/material.io)--><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" id=\"format_quote\" viewbox=\"0 0 512 512\"><path d=\"M299 363l42-86h-64V149h128v128l-42 86h-64zm-171 0l43-86h-64V149h128v128l-43 86h-64z\"><\/path><\/svg><\/span><\/div>\n              <\/div>\n            <\/div>\n          <\/div>\n          <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-7112-outer style-local-13496-c46-outer\">\n            <div data-colibri-id=\"13496-c46\" class=\"d-flex h-flex-basis h-column__inner h-px-lg-0 h-px-md-0 h-px-0 v-inner-lg-0 v-inner-md-0 v-inner-0 style-7112 style-local-13496-c46 position-relative\">\n              <!---->\n              <!---->\n              <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-center align-self-md-center align-self-center\">\n                <!---->\n                <div data-colibri-id=\"13496-c47\" class=\"h-text h-text-component style-7117 style-local-13496-c47 position-relative h-element\">\n                  <!---->\n                  <!---->\n                  <div class=\"\">\n                    <p>Biology is incredibly messy and complex. Wherever one looks, one can find inspiration by just wondering: \u201chow\"? I still remember the wonder and elation when I saw for the first time how cells self-organized into a network in a model experiment of blood vessel formation in vitro. To me, Physics is all about answering the question of \u201chow\u201d. Of course, the resulting models themselves can be challenging, interesting, and rewarding in their own right. But ultimately, the point is that Physics is tailored to distill minimal principles that convey some truth about a potentially very complex system. Oversimplification is an important feature of this process, because it allows us to develop an intuitive understanding that could lead to a change in perspective. In the same vein, model failure is not a bug but instead teaches us what we have neglected to account for, thereby providing a systematic way of increasing model complexity. Having narrowed down the physical principles, I think that machine learning provides an opportunity to scale up and screen large and interconnected datasets. I am really excited to discuss with the other members of CAIMed where this reductionist approach could be helpful or could benefit from other perspectives.<\/p>\n                  <\/div>\n                <\/div>\n              <\/div>\n            <\/div>\n          <\/div>\n        <\/div>\n      <\/div>\n      <div data-colibri-id=\"13496-c48\" class=\"h-row-container gutters-row-lg-0 gutters-row-md-0 gutters-row-0 gutters-row-v-lg-0 gutters-row-v-md-0 gutters-row-v-0 style-7109 style-local-13496-c48 position-relative\">\n        <!---->\n        <div class=\"h-row justify-content-lg-center justify-content-md-center justify-content-center align-items-lg-stretch align-items-md-stretch align-items-stretch gutters-col-lg-0 gutters-col-md-0 gutters-col-0 gutters-col-v-lg-0 gutters-col-v-md-0 gutters-col-v-0\">\n          <!---->\n          <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-7110-outer style-local-13496-c49-outer\">\n            <div data-colibri-id=\"13496-c49\" class=\"d-flex h-flex-basis h-column__inner h-px-lg-2 h-px-md-2 h-px-2 v-inner-lg-2 v-inner-md-2 v-inner-2 style-7110 style-local-13496-c49 position-relative\">\n              <!---->\n              <!---->\n              <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-center align-self-md-center align-self-center\">\n                <!---->\n                <div data-colibri-id=\"13496-c50\" class=\"h-global-transition-all h-heading style-7111 style-local-13496-c50 position-relative h-element\">\n                  <!---->\n                  <div class=\"h-heading__outer style-7111 style-local-13496-c50\">\n                    <!---->\n                    <!---->\n                    <h4 class=\"\">3.<\/h4>\n                  <\/div>\n                <\/div>\n              <\/div>\n            <\/div>\n          <\/div>\n          <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-7112-outer style-local-13496-c51-outer\">\n            <div data-colibri-id=\"13496-c51\" class=\"d-flex h-flex-basis h-column__inner h-px-lg-0 h-px-md-0 h-px-0 v-inner-lg-0 v-inner-md-0 v-inner-0 style-7112 style-local-13496-c51 position-relative\">\n              <!---->\n              <!---->\n              <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-center align-self-md-center align-self-center\">\n                <!---->\n                <div data-colibri-id=\"13496-c52\" class=\"h-global-transition-all h-heading style-7113 style-local-13496-c52 position-relative h-element\">\n                  <!---->\n                  <div class=\"h-heading__outer style-7113 style-local-13496-c52\">\n                    <!---->\n                    <!---->\n                    <h4 class=\"\">What opportunities does CAIMed offer for the transfer of AI into clinical practice?<\/h4>\n                  <\/div>\n                <\/div>\n              <\/div>\n            <\/div>\n          <\/div>\n        <\/div>\n      <\/div>\n      <div data-colibri-id=\"13496-c53\" class=\"h-row-container gutters-row-lg-0 gutters-row-md-0 gutters-row-0 gutters-row-v-lg-0 gutters-row-v-md-0 gutters-row-v-0 style-7114 style-local-13496-c53 position-relative\">\n        <!---->\n        <div class=\"h-row justify-content-lg-center justify-content-md-center justify-content-center align-items-lg-stretch align-items-md-stretch align-items-stretch gutters-col-lg-0 gutters-col-md-0 gutters-col-0 gutters-col-v-lg-0 gutters-col-v-md-0 gutters-col-v-0\">\n          <!---->\n          <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-7115-outer style-local-13496-c54-outer\">\n            <div data-colibri-id=\"13496-c54\" class=\"d-flex h-flex-basis h-column__inner h-px-lg-0 h-px-md-0 h-px-0 v-inner-lg-0 v-inner-md-0 v-inner-0 style-7115 style-local-13496-c54 position-relative\">\n              <!---->\n              <!---->\n              <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-start align-self-md-start align-self-start\">\n                <!---->\n                <div data-colibri-id=\"13496-c55\" class=\"h-icon style-7116 style-local-13496-c55 position-relative h-element\">\n                  <!----><span class=\"h-svg-icon h-icon__icon style-7116-icon style-local-13496-c55-icon\"><!--Icon by Material Icons (https:\/\/material.io)--><svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" id=\"format_quote\" viewbox=\"0 0 512 512\"><path d=\"M299 363l42-86h-64V149h128v128l-42 86h-64zm-171 0l43-86h-64V149h128v128l-43 86h-64z\"><\/path><\/svg><\/span><\/div>\n              <\/div>\n            <\/div>\n          <\/div>\n          <div class=\"h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-7112-outer style-local-13496-c56-outer\">\n            <div data-colibri-id=\"13496-c56\" class=\"d-flex h-flex-basis h-column__inner h-px-lg-0 h-px-md-0 h-px-0 v-inner-lg-0 v-inner-md-0 v-inner-0 style-7112 style-local-13496-c56 position-relative\">\n              <!---->\n              <!---->\n              <div class=\"w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-center align-self-md-center align-self-center\">\n                <!---->\n                <div data-colibri-id=\"13496-c57\" class=\"h-text h-text-component style-7117 style-local-13496-c57 position-relative h-element\">\n                  <!---->\n                  <!---->\n                  <div class=\"\">\n                    <p>One particular example that I have in mind is strongly related to a project and a question that I had for some time. Some viral proteins localize to specific regions in the cell such as the nucleolus or transcriptional condensates. In other pathologies, mutations or misregulation lead to aberrant localization of proteins. I think that it would be fantastic to better understand the principles and molecular features that underlie protein localization. This understanding could help guide, for example, drug interventions. This is a problem that is strongly related to thermodynamics and statistical mechanics (e.g., chemical potentials and molecular interactions), chemistry (e.g., protonation and deprotonation depending on pH), protein folding (where AI is state of the art), and is incredibly diverse and complex (there are thousands of different protein types that have been found in the nucleolus alone). I envision that my research group in CAIMed will tackle this challenge by combining detailed simulations (coarse-grained molecular dynamics) with machine learning to extract molecular features and biophysical modeling based on first principles.<\/p>\n                  <\/div>\n                <\/div>\n              <\/div>\n            <\/div>\n          <\/div>\n        <\/div>\n      <\/div>\n    <\/div>\n  <\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>3 Fragen an&#8230; Prof. Dr. Andriy Goychuk Gruppenleiter Prof. Dr. Andriy Goychuk erforscht die Selbstorganisation lebender Materie \u00fcber verschiedene Skalen hinweg \u2013 von Entz\u00fcndungsprozessen und Zelldynamiken auf Gewebeebene bis hin zur Organisation im Zellkern und den Dynamiken von Proteinen. Ein Schwerpunkt seiner Arbeit liegt in der Entwicklung numerischer Verfahren und theoretischer Modelle, die auf Biophysik, [&hellip;]<\/p>","protected":false},"author":13,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-templates\/full-width-page.php","meta":{"footnotes":""},"class_list":["post-13496","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/caimed.de\/en\/wp-json\/wp\/v2\/pages\/13496","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/caimed.de\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/caimed.de\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/caimed.de\/en\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/caimed.de\/en\/wp-json\/wp\/v2\/comments?post=13496"}],"version-history":[{"count":2,"href":"https:\/\/caimed.de\/en\/wp-json\/wp\/v2\/pages\/13496\/revisions"}],"predecessor-version":[{"id":13500,"href":"https:\/\/caimed.de\/en\/wp-json\/wp\/v2\/pages\/13496\/revisions\/13500"}],"wp:attachment":[{"href":"https:\/\/caimed.de\/en\/wp-json\/wp\/v2\/media?parent=13496"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}